Which part of the brain is primarily affected by THC in marijuana?

The hippcampus is primarily affected by THC in marijuana because it plays a crucial role in memory and learning processes. When THC, the psychoactive compound in marijuana, binds to cannabinoid receptors in the hippocampus, it alters synaptic transmission and affects the formation and retrieval of memories. This interaction can lead to short-term memory impairment, which is commonly reported by individuals under the influence of marijuana.

Additionally, the hippocampus is rich in receptors that interact with cannabinoids, making it a significant area of interest for understanding how THC influences cognitive functions. Consequently, the impact on the hippocampus explains many of the cognitive effects associated with marijuana use, such as altered perception and difficulties with memory formation.